Shutter Island opens this Friday, and a lof of folks are probably wondering how director Martin Scorsese -- who's tackled all kinds of film genres in his forty-plus year career -- will handle a traditional thriller. Having seen the film, I can say that despite what its trailer promises, it's pretty far from traditional, but still terrific; and it wears its genre influences proudly on its sleeve. (In fact, with apologies to The Departed, I think the film is probably Scorses's best since Casino.) Of course, the Oscar-winning filmmaker isn't exactly a stranger to our neck of the woods. His Cape Fear was a pretty straightforward excursion into terror, and, upon close inspection, his entire oeuvre is littered with moments scarier than what's offered by most of today's horror movies. So in honor of Shutter Island, we here at FEARnet present the twelve Scariest  Moments in Martin Scorsese Movies. Why only twelve, instead of the more frightening number that follows it? Because you, dear reader, are hereby invited to vote for your own after you watch Shutter Island this weekend. It's bound to give you a few chilling ideas.

Mean Street's Charlie (as played by Harvey Keitel) is a small-time hood whose girlfriend Teresa has epilepsy. When she suffers a sudden, horrifying seizure it forshadows the way in which his world will soon collapse.

Robert De Niro's Travis Bickle is, in Taxi Driver, one of the screen's most iconic anti-heroes. After Bickle goes on his climactic shooting spree to "save" Iris (Jodie Foster) from a life as a child prostitute, he looks at the last man standing, points a bloody finger at his head and smiles, an act more chilling than any that precedes it.

Raging Bull may be Scorsese's most acclaimed film. And deservedly so, because Robert De Niro makes real-life boxer Jake La Motta as frightening a monster as any to headline a horror flick. Especially when he assaults his brother Joey (played by Joe Pesci) after he mistakenly suspects him of sleeping with his wife.

Masha (played by Sandra Bernhard) decides to initiate a relationship with talk-show host Jerry Langford (played by funnyman Jerry Lewis) in King of Comedy. How? By kidnapping him, tying him up and going completely bugfuck insane on their first "date".

There are plenty of terrifying moments in After Hours, the tale of an ordinary guy (played by Griffin Dunne) who gets involved with a lot of extraordinary weirdness one night in New York City. But the top moment must be when Dunne, at the end of his rope, is turned into a piece of art by a deranged sculptor.

"What do you mean I'm funny?" Tommy (Joe Pesci) takes out his frustration with made man Henry's (Ray Liotta) observation by shooting Spider (Michael Imperioli) in the foot in Goodfellas. Makes perfect sense.

Robert DeNiro's psychopathic ex-con Max Cady is a walking time bomb in Cape Fear. He goes off big time when, attempting to get revenge on his former attorney, he picks up his mistress (Illeana Douglas) in a bar, takes her to bed, and proceeds to bite her cheek off.

Terror can take many forms. Sometimes its big, brutal and bloody. But it can be just as effective when it's small, quiet and subtle. Like the kind Newland Archer (Daniel Day-Lewis) experiences in The Age of Innocence when, just as he's about to tell his shallow fiancee May (played by Winona Ryder) that he's leaving her for the woman he really loves, he's told that she's pregnant, which means he'll be trapped in a loveless marriage to her for the rest of his life.

The only thing worse than dying is watching your loved ones die first, as Joe Pesci's Nicky Santoro learns when he watches his brother get murdered, before he himself is beaten to death with a baseball bat in Casino.

Nicholas Cage plays an ambulance driver whose night goes from bad to worse when he has to save a junkie who's accidentally impaled himself on a spiked fence in Bringing Out the Dead. So chilling it's kind of hilarious.

Few things are as frightening as losing one's mind. As Leonardo Di Caprio's Howard Hughes proves when the millionaire genius becomes a shut-in and starts collecting bottles of his own urine in The Aviator.

Di Caprio's Billy Costigan experiences another kind of madness when his boss/father figure cop (played by Martin Sheen) is thrown off a building by the same mobsters Billy's been assigned to work with, in Scorsese's last film, the Oscar-winning The Departed.